Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species
Authors
Pajić, MarkoAleksić, Nevenka

Vejnović, Branislav

Polaček, Vladimir
Novakov, Nikolina
Ostojić Andrić, Dušica

Stanimirović, Zoran

Article (Published version)
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The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two
untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine,
the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on
day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST),
and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram,
and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05),
whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to th...ose untreated. The most prominent
change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly
higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and
Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects
Keywords:
Broilers / ROS / Coccidia / Robenidine / Herbal anticoccidialSource:
Kafkas Universitesi Veteriner Fakultesi Dergisi, 2018, 25, 3, 379-385Publisher:
- Kafkas Univ Vet Fak Derg
Funding / projects:
- Research on pharmacological characteristics of antimicrobial agents, introduction of new technological solutions and alternative prophylactic methods with the purpose to improve control of infectious animal disease (RS-31071)
- Molecular genetic and ecophysiological researches on the protection of autochthonous animal genetic resources, sustaining domestic animals’ welfare, health and reproduction, and safe food production (RS-46002)
DOI: 10.9775/kvfd.2018.21021
ISSN: 1300-6045
WoS: 000460503100014
Scopus: 2-s2.0-85067499046
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RIStocarTY - JOUR AU - Pajić, Marko AU - Aleksić, Nevenka AU - Vejnović, Branislav AU - Polaček, Vladimir AU - Novakov, Nikolina AU - Ostojić Andrić, Dušica AU - Stanimirović, Zoran PY - 2018 UR - http://r.istocar.bg.ac.rs/handle/123456789/652 AB - The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine, the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST), and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram, and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05), whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to those untreated. The most prominent change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects PB - Kafkas Univ Vet Fak Derg T2 - Kafkas Universitesi Veteriner Fakultesi Dergisi T1 - Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species VL - 25 IS - 3 SP - 379 EP - 385 DO - 10.9775/kvfd.2018.21021 ER -
@article{ author = "Pajić, Marko and Aleksić, Nevenka and Vejnović, Branislav and Polaček, Vladimir and Novakov, Nikolina and Ostojić Andrić, Dušica and Stanimirović, Zoran", year = "2018", abstract = "The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine, the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST), and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram, and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05), whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to those untreated. The most prominent change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects", publisher = "Kafkas Univ Vet Fak Derg", journal = "Kafkas Universitesi Veteriner Fakultesi Dergisi", title = "Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species", volume = "25", number = "3", pages = "379-385", doi = "10.9775/kvfd.2018.21021" }
Pajić, M., Aleksić, N., Vejnović, B., Polaček, V., Novakov, N., Ostojić Andrić, D.,& Stanimirović, Z.. (2018). Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species. in Kafkas Universitesi Veteriner Fakultesi Dergisi Kafkas Univ Vet Fak Derg., 25(3), 379-385. https://doi.org/10.9775/kvfd.2018.21021
Pajić M, Aleksić N, Vejnović B, Polaček V, Novakov N, Ostojić Andrić D, Stanimirović Z. Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species. in Kafkas Universitesi Veteriner Fakultesi Dergisi. 2018;25(3):379-385. doi:10.9775/kvfd.2018.21021 .
Pajić, Marko, Aleksić, Nevenka, Vejnović, Branislav, Polaček, Vladimir, Novakov, Nikolina, Ostojić Andrić, Dušica, Stanimirović, Zoran, "Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species" in Kafkas Universitesi Veteriner Fakultesi Dergisi, 25, no. 3 (2018):379-385, https://doi.org/10.9775/kvfd.2018.21021 . .