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dc.creatorMuñoz, M.
dc.creatorBozzi, Riccardo
dc.creatorGarcía, F.
dc.creatorNuñez, Yolanda
dc.creatorGeraci, Claudia
dc.creatorCrovetti, Alessandro
dc.creatorGarcia Casco, Juan Maria
dc.creatorAlves, Estefânia
dc.creatorŠkrlep, M.
dc.creatorCharneca, Rui
dc.creatorMartins, J.M.
dc.creatorQuintanilla, R.
dc.creatorTibau, J.
dc.creatorKušec, Goran
dc.creatorDjurkin-Kušec, I.
dc.creatorMercat, Marie-José
dc.creatorRiquet, J.
dc.creatorEstellé, J.
dc.creatorZimmer, C.
dc.creatorRazmaite, V.
dc.creatorAraujo, José Pedro
dc.creatorRadović, Čedomir
dc.creatorSavić, Radomir
dc.creatorKarolyi, Danijel
dc.creatorGallo, Maurizio
dc.creatorČandek-Potokar, Marjeta
dc.creatorFontanesi, Luca
dc.creatorFernández, A.I.
dc.creatorÓvilo, C.
dc.date.accessioned2018-12-14T15:14:22Z
dc.date.available2018-12-14T15:14:22Z
dc.date.issued2018
dc.identifier.issn1932-6203
dc.identifier.urihttp://r.istocar.bg.ac.rs/handle/123456789/551
dc.identifier.urihttp://hdl.handle.net/20.500.12327/251
dc.description.abstractThe aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds. Also, the potential of the SNP panel employed for elucidating the genetic structure and relationships among breeds was evaluated. Most relevant genes and mutations associated with pig morphological, productive, meat quality, reproductive and disease resistance traits were prioritized and analyzed in a maximum of 47 blood samples from each of the breeds (Alentejana, Apulo-Calabrese, Basque, Bísara, Majorcan Black, Black Slavonian (Crna slavonska), Casertana, Cinta Senese, Gascon, Iberian, Krškopolje (Krškopoljski), Lithuanian indigenous wattle, Lithuanian White Old Type, Mora Romagnola, Moravka, Nero Siciliano, Sarda, Schwäbisch-Hällisches Schwein (Swabian Hall pig), Swallow-Bellied Mangalitsa and Turopolje). We successfully analyzed allelic variation in 39 polymorphisms, located in 33 candidate genes. Results provide relevant information regarding genetic diversity and segregation of SNPs associated to production and quality traits. Coat color and morphological trait-genes that show low level of segregation, and fixed SNPs may be useful for traceability. On the other hand, we detected SNPs which may be useful for association studies as well as breeding programs. For instance, we observed predominance of alleles that might be unfavorable for disease resistance and boar taint in most breeds and segregation of many alleles involved in meat quality, fatness and growth traits. Overall, these findings provide a detailed catalogue of segregating candidate SNPs in 20 European local pig breeds that may be useful for traceability purposes, for association studies and for breeding schemes. Population genetic analyses based on these candidate genes are able to uncover some clues regarding the hidden genetic substructure of these populations, as the extreme genetic closeness between Iberian and Alentejana breeds and an uneven admixture of the breeds studied. The results are in agreement with available knowledge regarding breed history and management, although largest panels of neutral markers should be employed to get a deeper understanding of the population's structure and relationships.en
dc.publisherPublic Library of Science (PLoS)
dc.relationinfo:eu-repo/grantAgreement/EC/H2020/634476/EU//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourcePloS one
dc.titleDiversity across major and candidate genes in European local pig breedsen
dc.typearticle
dc.rights.licenseBY
dcterms.abstractГераци, Ц.; Гарцíа, Ф.; Aлвес, Е.; Гарцíа-Цасцо, Ј.; Цхарнеца, Р.; Цроветти, A.; Чандек-Потокар, М.; Муñоз, М.; Боззи, Р.; Нúñез, Y.; Óвило, Ц.; Кушец, Г.; Мерцат, М.Ј.; Aраујо, Ј.П.; Радовић, Чедомир; Савић, Радомир; Каролyи, Д.; Фернáндез, A.И.; Фонтанеси, Л.; Галло, М.; Размаите, В.; Зиммер, Ц.; Естеллé, Ј.; Риqует, Ј.; Дјуркин-Кушец, И.; Тибау, Ј.; Qуинтанилла, Р.; Мартинс, Ј.М.; Шкрлеп, М.;
dc.citation.volume13
dc.citation.issue11
dc.citation.other13(11): -
dc.citation.rankM21
dc.identifier.pmid30458028
dc.identifier.doi10.1371/journal.pone.0207475
dc.identifier.fulltexthttp://r.istocar.bg.ac.rs//bitstream/id/2286/549.pdf
dc.identifier.scopus2-s2.0-85056802424
dc.identifier.wos000450775300019
dc.type.versionpublishedVersion


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