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dc.creatorÓvilo, Cristina
dc.creatorBozzi, Riccardo
dc.creatorGarcía, F.
dc.creatorNuñez, Yolanda
dc.creatorGeraci, Claudia
dc.creatorCrovetti, Alessandro
dc.creatorGarcia Casco, Juan Maria
dc.creatorAlves, Estefânia
dc.creatorŠkrlep, Martin
dc.creatorCharneca, Rui
dc.creatorQuintanilla, Raquel
dc.creatorKušec, Goran
dc.creatorRiquet, Juliette
dc.creatorMercat, Marie-José
dc.creatorZimmer, Christoph
dc.creatorRazmaitė, Violeta
dc.creatorAraujo, José Pedro
dc.creatorRadović, Čedomir
dc.creatorSavić, Radomir
dc.creatorČandek-Potokar, Marjeta
dc.creatorFontanesi, Luca
dc.creatorFernández, Ana
dc.creatorMuñoz, Maria
dc.date.accessioned2018-10-09T20:48:33Z
dc.date.accessioned2018-12-18T16:31:36Z
dc.date.available2018-10-09T20:48:33Z
dc.date.available2018-12-18T16:31:36Z
dc.date.issued2017
dc.identifier.isbn978-84-697-7375-8
dc.identifier.urihttps://zenodo.org/record/1135160
dc.identifier.urihttp://epserbia.open.ac.rs/123456789/196
dc.identifier.urihttp://r.istocar.bg.ac.rs/handle/123456789/572
dc.description.abstractIn the frame of the European TREASURE* project, the genetic characterization of 20 local pig breeds is being performed with genetic and genomic tools. The objectives are the study of genetic diversity in these populations and the identification of useful markers for authentication, traceability, conservation and breeding programs. In first place, a candidate gene approach has been applied and the most relevant genes and mutations associated with pig productive, meat quality, reproductive and disease resistance traits have been prioritized and analyzed. Two OpenArray® chips of 32 and 16 SNPs were designed and genotyped in 48 animals from each one of 20 breeds included in the project (Alentejana, Apulo Calabrese, Basque, Bísaro, Black Majorcan, Black Sicilian, Black Slavonian, Casertana, Cinta Senese, Gascon, Iberian, Krskopolje, Lithuanian indigenous wattle, Mangalitsa, Mora Romagnola, Moravka, Old Lithuanian White, Sarda, Schwäbisch Hällisches, Turopolje). Forty SNPs located in 34 genes were successfully genotyped (MC1R, TYRP1, NR6A, PCK1, RYR1, IGF2, MC4R, PHKG1, SCD, GBP5, TAS2R39, TAS2R4, MUC4, ESR1, CYP2E1, LEP, CAST, MTTP, CYB5A, FTO, PPARGC1A, CAPN1, PPARD, CTSL, LEPR, PRKAG3, ACACA, KIT, ACSL4, ADIPOQ, FASN, AHR, FUT1, MSTN). Results provide relevant information regarding genetic diversity and segregation of SNPs responsible for specific production and quality traits. Coat color and morphological trait-genes, showing low level of segregation, and fixed SNPs may be useful for traceability. On the other hand, we detected SNPs which may be useful for breeding programs. For instance, we observed predominance of unfavorable alleles for disease resistance and boar taint genes in most breeds, and segregation of many genes involved in meat quality, fatness and growth. These results joint with ongoing genomic assays, will provide essential information regarding genetic diversity, structure, selective signatures and biological processes responsible for specific production and quality traits.en
dc.languageen
dc.publisherBadajoz : CICYTEX
dc.relationinfo:eu-repo/grantAgreement/EC/H2020/634476/EU//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceBook of Abstracts of the 4th Fatty Pig Science and Utilization International Conference
dc.subjectfatty pigs
dc.subjectcandidate gene
dc.subjectallele frequency
dc.subjectgenetic characterization
dc.subjectlocal pig breeds
dc.subjectgenetic diversity
dc.titleDiversity across Major and Candidate Genes in European Local Pig Breedsen
dc.typeconferenceObject
dc.rights.licenseBY
dcterms.abstractМерцат, Марие-Јосé; Зиммер, Цхристопх; Размаитė, Виолета; Фонтанеси, Луца; Фернáндез, Aна; Муñоз, Мариа; Aраúјо, Јосé Педро; Боззи, Риццардо; Гарцíа, Ф.; Гераци, Цлаудиа; Шкрлеп, Мартин; Цхарнеца, Руи; Qуинтанилла, Раqуел; Радовић, Чедомир; Савић, Радомир; Чандек-Потокар, Марјета; Óвило, Цристина; Нуñез, Yоланда; Цроветти, Aлессандро; Гарцíа-Цасцо, Јуан; Aлвес, Естефâниа; Кушец, Горан; Риqует, Јулиетте;
dc.citation.spage51
dc.citation.epage52
dc.identifier.doi10.5281/zenodo.1135160
dc.identifier.fulltexthttp://r.istocar.bg.ac.rs/bitstream/id/1537/bitstream_1537.pdf


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