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dc.creatorTrukhachev, Vladimir
dc.creatorBelyaev, Valery
dc.creatorKvochko, Andrey
dc.creatorKulichenko, Alexander
dc.creatorKovalev, Dmitry
dc.creatorPisarenko, Sergey
dc.creatorVolynkina, Anna
dc.creatorSelionova, Marina
dc.creatorAybazov, Magomet M.
dc.creatorShumaenko, Svetlana
dc.creatorOmarov, Arslan
dc.creatorMamontova, Tatyana
dc.creatorYatsyk, Olesya
dc.creatorKrivoruchko, Alexander
dc.creatorPetrović, Milan P.
dc.creatorPantelić, Vlada
dc.creatorCaro Petrović, Violeta
dc.date.accessioned2018-12-14T15:09:38Z
dc.date.available2018-12-14T15:09:38Z
dc.date.issued2016
dc.identifier.issn0534-0012
dc.identifier.urihttp://r.istocar.bg.ac.rs/handle/123456789/480
dc.description.abstractOne of the new promising candidate genes defining productive qualities of sheep is MEF2B. Protein from the MEF2 group encoded by it affects the production of myostatin and the expression of the genes responsible for the growth of skeletal muscle fibers. Thus, the knowledge of the MEF2B gene structure is important for genomic selection. We have studied the structure of the MEF2B gene at sheep of Severokavkazskaya breed bred in Russia. To detect alleles we use NimbleGen sequencing technology by Roche (USA). As a result, it was revealed 14 single nucleotide polymorphisms (SNP) at the given breed. The discovered SNPare located in not coding areas. From them 7 polymorphisms are in the area of 5' upstream gene in loci: c.-1713, c.-1319, c.-839, c.-321, c.-246, c.-161, c.-3; 6 polymorphisms are in introns, loci: c.55-51, c.258+312, c.258+380, c.259-52, c.452+95, c.452+ 103, 1 SNP is in 3' downstream gene, c.*252. Two of the identified SNPs are significantly connected with high indices of meat productivity: c.55-51 and c.259-52. At the same time it was not possible to find out the impact on productivity of c.-1713 polymorphism. Our investigation is a base of next research of affection of different MEF2B gene alleles on meat quality and can be used to prepare PCR test-system for genomic selection.en
dc.publisherSerbian Genetics Society, Belgrade
dc.relationMinistry of Agriculture of the Russian Federation [3119/13]
dc.rightsopenAccess
dc.sourceGenetika-Belgrade
dc.subjectgenomic electionen
dc.subjectMEF2Ben
dc.subjectsequenceen
dc.subjectsheepen
dc.subjectSNPen
dc.titleMef2b gene snp markers of meat productivity in Severokavkazskaya sheep breeden
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractМамонтова, Татyана; Трукхацхев, Владимир; Белyаев, Валерy; Квоцхко, Aндреy; Кулицхенко, Aлеxандер; Ковалев, Дмитрy; Писаренко, Сергеy; Волyнкина, Aнна; Селионова, Марина; Ayбазов, Магомет; Схумаенко, Светлана; Омаров, Aрслан; Yатсyк, Олесyа; Криворуцхко, Aлеxандер; Царо-Петровић, Виолета; Пантелић, Влада; Петровић, Милан П.;
dc.citation.volume48
dc.citation.issue1
dc.citation.spage97
dc.citation.epage108
dc.citation.other48(1): 97-108
dc.citation.rankM23
dc.identifier.doi10.2298/GENSR1601097T
dc.identifier.rcubKonv_83
dc.identifier.fulltexthttp://r.istocar.bg.ac.rs//bitstream/id/2222/478.pdf
dc.identifier.scopus2-s2.0-84971264763
dc.identifier.wos000376744800009
dc.type.versionpublishedVersion


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