TY  - JOUR
AU  - Đurđević, Biljana
AU  - Pajić, Marko
AU  - Knežević, Slobodan
AU  - Polaček, Vladimir
AU  - Nešić, Ksenija
AU  - Vučićević, Ivana
AU  - Ostojić Andrić, Dušica
PY  - 2022
UR  - http://r.istocar.bg.ac.rs/handle/123456789/821
AB  - This experiment was performed to investigate the protective effect of a new combined adsorbent (bentonite + yeast cell 
wall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with aflatoxin
B1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control),
group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2  mg/kg aflatoxin B1), and group IV (2 mg/kg aflatoxin B1). Grossly,
AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleen
revealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions were
observed in aflatoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclear
cells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis and infiltration of mononuclear
cells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in the
duodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealed
that supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorate
aflatoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% aflatoxin binding
efficiency in in vitro study.
T2  - Kafkas Universitesi Veteriner Fakültesi Dergisi
T1  - Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens.
VL  - 28
IS  - 2
SP  - 185
EP  - 191
DO  - 10.9775/kvfd.2021.26654
ER  - 

@article{
author = "Đurđević, Biljana and Pajić, Marko and Knežević, Slobodan and Polaček, Vladimir and Nešić, Ksenija and Vučićević, Ivana and Ostojić Andrić, Dušica",
year = "2022",
abstract = "This experiment was performed to investigate the protective effect of a new combined adsorbent (bentonite + yeast cell 
wall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with aflatoxin
B1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control),
group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2  mg/kg aflatoxin B1), and group IV (2 mg/kg aflatoxin B1). Grossly,
AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleen
revealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions were
observed in aflatoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclear
cells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis and infiltration of mononuclear
cells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in the
duodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealed
that supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorate
aflatoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% aflatoxin binding
efficiency in in vitro study.",
journal = "Kafkas Universitesi Veteriner Fakültesi Dergisi",
title = "Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens.",
volume = "28",
number = "2",
pages = "185-191",
doi = "10.9775/kvfd.2021.26654"
}

Đurđević, B., Pajić, M., Knežević, S., Polaček, V., Nešić, K., Vučićević, I.,& Ostojić Andrić, D.. (2022). Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens.. in Kafkas Universitesi Veteriner Fakültesi Dergisi, 28(2), 185-191.
https://doi.org/10.9775/kvfd.2021.26654

Đurđević B, Pajić M, Knežević S, Polaček V, Nešić K, Vučićević I, Ostojić Andrić D. Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens.. in Kafkas Universitesi Veteriner Fakültesi Dergisi. 2022;28(2):185-191.
doi:10.9775/kvfd.2021.26654 .

Đurđević, Biljana, Pajić, Marko, Knežević, Slobodan, Polaček, Vladimir, Nešić, Ksenija, Vučićević, Ivana, Ostojić Andrić, Dušica, "Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1‐Challenged Broiler Chickens." in Kafkas Universitesi Veteriner Fakültesi Dergisi, 28, no. 2 (2022):185-191,
https://doi.org/10.9775/kvfd.2021.26654 . .

TY  - JOUR
AU  - Pajić, Marko
AU  - Aleksić, Nevenka
AU  - Vejnović, Branislav
AU  - Polaček, Vladimir
AU  - Novakov, Nikolina
AU  - Ostojić Andrić, Dušica
AU  - Stanimirović, Zoran
PY  - 2018
UR  - http://r.istocar.bg.ac.rs/handle/123456789/652
AB  - The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two
untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine,
the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on
day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST),
and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram,
and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05),
whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to those untreated. The most prominent
change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly
higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and
Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects
PB  - Kafkas Univ Vet Fak Derg
T2  - Kafkas Universitesi Veteriner Fakultesi Dergisi
T1  - Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species
VL  - 25
IS  - 3
SP  - 379
EP  - 385
DO  - 10.9775/kvfd.2018.21021
ER  - 

@article{
author = "Pajić, Marko and Aleksić, Nevenka and Vejnović, Branislav and Polaček, Vladimir and Novakov, Nikolina and Ostojić Andrić, Dušica and Stanimirović, Zoran",
year = "2018",
abstract = "The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two
untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine,
the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on
day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST),
and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram,
and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P<0.05),
whilst the activity of SOD was higher in infected chickens treated with anticoccidials (P<0.05) in comparison to those untreated. The most prominent
change in the parameters of oxidative stress was recorded in the Ro+Herb group. In chickens treated with anticoccidials body weight was significantly
higher (P<0.05), and the FCR and the oocyst counts significantly lower (P<0.05) than in untreated chickens. Oocyst counts were lower in the Ro and
Ro+Herb groups than in the Herb group. Our study demonstrated that both anticoccidial substances exerted antioxidant and anticoccidial effects",
publisher = "Kafkas Univ Vet Fak Derg",
journal = "Kafkas Universitesi Veteriner Fakultesi Dergisi",
title = "Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species",
volume = "25",
number = "3",
pages = "379-385",
doi = "10.9775/kvfd.2018.21021"
}

Pajić, M., Aleksić, N., Vejnović, B., Polaček, V., Novakov, N., Ostojić Andrić, D.,& Stanimirović, Z.. (2018). Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species. in Kafkas Universitesi Veteriner Fakultesi Dergisi
Kafkas Univ Vet Fak Derg., 25(3), 379-385.
https://doi.org/10.9775/kvfd.2018.21021

Pajić M, Aleksić N, Vejnović B, Polaček V, Novakov N, Ostojić Andrić D, Stanimirović Z. Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species. in Kafkas Universitesi Veteriner Fakultesi Dergisi. 2018;25(3):379-385.
doi:10.9775/kvfd.2018.21021 .

Pajić, Marko, Aleksić, Nevenka, Vejnović, Branislav, Polaček, Vladimir, Novakov, Nikolina, Ostojić Andrić, Dušica, Stanimirović, Zoran, "Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species" in Kafkas Universitesi Veteriner Fakultesi Dergisi, 25, no. 3 (2018):379-385,
https://doi.org/10.9775/kvfd.2018.21021 . .