TY  - JOUR
AU  - Teneva, A.
AU  - Dimitrov, K.
AU  - Caro Petrović, Violeta
AU  - Petrović, Milan P.
AU  - Dimitrova, I.
AU  - Tyufekchiev, N.
AU  - Petrov, N.
PY  - 2013
UR  - http://r.istocar.bg.ac.rs/handle/123456789/396
AB  - Molecular genetics investigates the genetic makeup of individuals at the DNA level. That includes the identification and mapping of molecular genetic markers and genetic polymorphisms. Molecular genetic markers (DNA markers) are one of the most powerful means for the genomic analysis and allow the connection of hereditary traits with genomic variation. Molecular marker technology has developed rapidly over the last decade and two shapes of specific DNA based marker, Simple Sequence Repeats (SSRs), also known as microsatellites, and Single Nucleotide Polymorphisms (SNPs) prevail applications in modern genetic analysis. Genomic simple sequence repeats (SSRs, microsatellites) have been used for a variety of purposes, including gene tagging, physical mapping, genome mapping, estimation of genetic diversity, phylogenetic and conservation genetic purposes in farm animal breeding. SSR analyses are applied successfully in parentage verification and pedigree analysis, as disease markers and to locate the mutation in genetic disorders in livestock animals. The ultimate use of SSRs markers is for mapping quantitative trait loci (QTL), marker assisted selection (MAS) in order to practice genomic selection and improve the farm animal health. Developments in 'omics' technologies, such as genomic selection, may help overcome several of the limitations of traditional breeding programmes and will be especially beneficial in breeding for lowly heritable disease traits that only manifest themselves following exposure to pathogens or environmental stressors in adulthood. The current paper provides a brief overview of the present - day application of microsatellites markers in animal breeding and make significant contribution to the overall farm animal health and resistance to disease.
AB  - Molekularna genetika istražuje genetski sastav pojedinaca na nivou DNK. To uključuje identifikaciju i mapiranje molekularnih genetskih markera i genetskih polimorfizama. Molekularni genetski markeri (DNK markeri) su jedan od najmoćnijih sredstava genomske analize i pružaju mogućnost povezivanja naslednih osobina sa genomskim varijacijama. Tehnologija molekularnih markera se brzo razvila u poslednjoj deceniji, a dva oblika markera na bazi DNK, Simple Sequence Repeats (SSR), takođe poznati kao mikrosateliti, i polimorfizam pojedinačnih nukleotida - Single Nucleotide Polymorphisms (SNP) preovlađuju u primeni u modernoj genetskoj analizi. Genomske sekvence - ponavljanja (Simple Sequence Repeats - SSR, mikrosateliti) se koriste za razne svrhe, uključujući označavanje gena, fizičko mapiranje, mapiranje genoma, procena genetičke raznovrsnosti, filogenetske i u svrhu genetičke konzervacije u uzgoju farmskih životinja. SSR analiza se uspešno primenjuju u verifikaciji roditeljstva, i analizi pedigrea, kao markeri bolesti i u pronalaženju mutacije i genetskih poremećaja kod farmskih životinja. Krajnja upotreba SSR markera je za mapiranje lokusa kvantitativnih osobina (QTL), selekciji pomoću markera (MAS), kako bi se u praksi primenjivala genomska selekciju i unapređenje zdravlja farmskih životinja. Razvoj u tehnologijama 'omics'', kao što je genomska selekcija, može pomoći u prevazilaženju nekoliko ograničenja tradicionalnih odgajivačkih programa a posebno će biti korisna za oplemenjivanje i odgoj na nižu naslednost naslednih osobina bolesti koje se ispoljavaju tek nakon izloženosti patogenima ili ekološkim stresorima u odraslom dobu. Ovaj rad daje kratak pregled današnje primene mikrosatelit markera u stočarstvu i daje značajan doprinos ukupnom zdravlju životinja uzgajanih na farmi i otpornosti na bolesti.
PB  - Institute for Animal Husbandry, Belgrade
T2  - Biotechnology in Animal Husbandry
T1  - Molecular genetics and SSR markers as a new practice in farm animal genomic analysis for breeding and control of disease disorders
T1  - Molekularna genetika i SSR markeri kao nova praksa u genomskoj analizi farmskih životinja u reprodukciji i kontroli bolesti
VL  - 29
IS  - 3
SP  - 405
EP  - 429
DO  - 10.2298/BAH1303405T
ER  - 

@article{
author = "Teneva, A. and Dimitrov, K. and Caro Petrović, Violeta and Petrović, Milan P. and Dimitrova, I. and Tyufekchiev, N. and Petrov, N.",
year = "2013",
abstract = "Molecular genetics investigates the genetic makeup of individuals at the DNA level. That includes the identification and mapping of molecular genetic markers and genetic polymorphisms. Molecular genetic markers (DNA markers) are one of the most powerful means for the genomic analysis and allow the connection of hereditary traits with genomic variation. Molecular marker technology has developed rapidly over the last decade and two shapes of specific DNA based marker, Simple Sequence Repeats (SSRs), also known as microsatellites, and Single Nucleotide Polymorphisms (SNPs) prevail applications in modern genetic analysis. Genomic simple sequence repeats (SSRs, microsatellites) have been used for a variety of purposes, including gene tagging, physical mapping, genome mapping, estimation of genetic diversity, phylogenetic and conservation genetic purposes in farm animal breeding. SSR analyses are applied successfully in parentage verification and pedigree analysis, as disease markers and to locate the mutation in genetic disorders in livestock animals. The ultimate use of SSRs markers is for mapping quantitative trait loci (QTL), marker assisted selection (MAS) in order to practice genomic selection and improve the farm animal health. Developments in 'omics' technologies, such as genomic selection, may help overcome several of the limitations of traditional breeding programmes and will be especially beneficial in breeding for lowly heritable disease traits that only manifest themselves following exposure to pathogens or environmental stressors in adulthood. The current paper provides a brief overview of the present - day application of microsatellites markers in animal breeding and make significant contribution to the overall farm animal health and resistance to disease., Molekularna genetika istražuje genetski sastav pojedinaca na nivou DNK. To uključuje identifikaciju i mapiranje molekularnih genetskih markera i genetskih polimorfizama. Molekularni genetski markeri (DNK markeri) su jedan od najmoćnijih sredstava genomske analize i pružaju mogućnost povezivanja naslednih osobina sa genomskim varijacijama. Tehnologija molekularnih markera se brzo razvila u poslednjoj deceniji, a dva oblika markera na bazi DNK, Simple Sequence Repeats (SSR), takođe poznati kao mikrosateliti, i polimorfizam pojedinačnih nukleotida - Single Nucleotide Polymorphisms (SNP) preovlađuju u primeni u modernoj genetskoj analizi. Genomske sekvence - ponavljanja (Simple Sequence Repeats - SSR, mikrosateliti) se koriste za razne svrhe, uključujući označavanje gena, fizičko mapiranje, mapiranje genoma, procena genetičke raznovrsnosti, filogenetske i u svrhu genetičke konzervacije u uzgoju farmskih životinja. SSR analiza se uspešno primenjuju u verifikaciji roditeljstva, i analizi pedigrea, kao markeri bolesti i u pronalaženju mutacije i genetskih poremećaja kod farmskih životinja. Krajnja upotreba SSR markera je za mapiranje lokusa kvantitativnih osobina (QTL), selekciji pomoću markera (MAS), kako bi se u praksi primenjivala genomska selekciju i unapređenje zdravlja farmskih životinja. Razvoj u tehnologijama 'omics'', kao što je genomska selekcija, može pomoći u prevazilaženju nekoliko ograničenja tradicionalnih odgajivačkih programa a posebno će biti korisna za oplemenjivanje i odgoj na nižu naslednost naslednih osobina bolesti koje se ispoljavaju tek nakon izloženosti patogenima ili ekološkim stresorima u odraslom dobu. Ovaj rad daje kratak pregled današnje primene mikrosatelit markera u stočarstvu i daje značajan doprinos ukupnom zdravlju životinja uzgajanih na farmi i otpornosti na bolesti.",
publisher = "Institute for Animal Husbandry, Belgrade",
journal = "Biotechnology in Animal Husbandry",
title = "Molecular genetics and SSR markers as a new practice in farm animal genomic analysis for breeding and control of disease disorders, Molekularna genetika i SSR markeri kao nova praksa u genomskoj analizi farmskih životinja u reprodukciji i kontroli bolesti",
volume = "29",
number = "3",
pages = "405-429",
doi = "10.2298/BAH1303405T"
}

Teneva, A., Dimitrov, K., Caro Petrović, V., Petrović, M. P., Dimitrova, I., Tyufekchiev, N.,& Petrov, N.. (2013). Molecular genetics and SSR markers as a new practice in farm animal genomic analysis for breeding and control of disease disorders. in Biotechnology in Animal Husbandry
Institute for Animal Husbandry, Belgrade., 29(3), 405-429.
https://doi.org/10.2298/BAH1303405T

Teneva A, Dimitrov K, Caro Petrović V, Petrović MP, Dimitrova I, Tyufekchiev N, Petrov N. Molecular genetics and SSR markers as a new practice in farm animal genomic analysis for breeding and control of disease disorders. in Biotechnology in Animal Husbandry. 2013;29(3):405-429.
doi:10.2298/BAH1303405T .

Teneva, A., Dimitrov, K., Caro Petrović, Violeta, Petrović, Milan P., Dimitrova, I., Tyufekchiev, N., Petrov, N., "Molecular genetics and SSR markers as a new practice in farm animal genomic analysis for breeding and control of disease disorders" in Biotechnology in Animal Husbandry, 29, no. 3 (2013):405-429,
https://doi.org/10.2298/BAH1303405T . .

TY  - JOUR
AU  - Caro Petrović, Violeta
AU  - Ilić, Zoran Z.
AU  - Teneva, A.
AU  - Petrović, Milan P.
AU  - Spasic, Z.L.J.
AU  - Petrović, Milan M.
AU  - Ružić-Muslić, Dragana
PY  - 2013
UR  - http://r.istocar.bg.ac.rs/handle/123456789/377
AB  - Data from the Pirot improved sheep were use to estimate postnatal development and growth traits relationship of lambs from birth to weaning. The experiment included 360 lambs, divided into three groups (I, II, III). Lamb traits included BW at birth and approximately 30d, 60d and 90d (weaning). Lambs managed under conditions typical of the area. Male lambs in-group I had a total gain of 22.97 kg (0.255 kg/d), in group II 25.97 kg (0.286 kg/d) (P (lt) 0.01). Lambs in-group III the total gain was 24.64 kg (0.274 kg/d), which was lower than lambs of group II (P>0.05). On the other side, III group of lambs had a higher gain than the I group (P (lt) 0.01). Development of female lambs in the postnatal period was slightly weaker. Lambs of I group, from birth to weaning had a total gain of 21.27 kg, (0.236 kg/d), II group was 23.32 kg (0.259 kg/d). The difference was statistically very significant (P (lt) 0.01). Lambs of group III had a total gain of 23.54 kg (0.261kg/d) and higher growth rate then lambs of group II, but not significant (P>0.05). From the other side, the difference in comparison with the groups III and I was very significant (P (lt) 0.01). Correlations between BWB and BW30, 60, 90 are ranged from low to moderate among the respective traits and ranged between positive from 0.001 to 0.365 and negative from -0.005 to -0.279. Can conclude that the selection should direct towards producing lambs with intermediate birth weight.
PB  - Scientific Issues Natl Centre Agrarian Sciences, Sofia
T2  - Bulgarian Journal of Agricultural Science
T1  - Study of the growth traits relationship of lambs in the postnatal development
VL  - 19
IS  - 4
SP  - 801
EP  - 805
UR  - https://hdl.handle.net/21.15107/rcub_ristocar_377
ER  - 

@article{
author = "Caro Petrović, Violeta and Ilić, Zoran Z. and Teneva, A. and Petrović, Milan P. and Spasic, Z.L.J. and Petrović, Milan M. and Ružić-Muslić, Dragana",
year = "2013",
abstract = "Data from the Pirot improved sheep were use to estimate postnatal development and growth traits relationship of lambs from birth to weaning. The experiment included 360 lambs, divided into three groups (I, II, III). Lamb traits included BW at birth and approximately 30d, 60d and 90d (weaning). Lambs managed under conditions typical of the area. Male lambs in-group I had a total gain of 22.97 kg (0.255 kg/d), in group II 25.97 kg (0.286 kg/d) (P (lt) 0.01). Lambs in-group III the total gain was 24.64 kg (0.274 kg/d), which was lower than lambs of group II (P>0.05). On the other side, III group of lambs had a higher gain than the I group (P (lt) 0.01). Development of female lambs in the postnatal period was slightly weaker. Lambs of I group, from birth to weaning had a total gain of 21.27 kg, (0.236 kg/d), II group was 23.32 kg (0.259 kg/d). The difference was statistically very significant (P (lt) 0.01). Lambs of group III had a total gain of 23.54 kg (0.261kg/d) and higher growth rate then lambs of group II, but not significant (P>0.05). From the other side, the difference in comparison with the groups III and I was very significant (P (lt) 0.01). Correlations between BWB and BW30, 60, 90 are ranged from low to moderate among the respective traits and ranged between positive from 0.001 to 0.365 and negative from -0.005 to -0.279. Can conclude that the selection should direct towards producing lambs with intermediate birth weight.",
publisher = "Scientific Issues Natl Centre Agrarian Sciences, Sofia",
journal = "Bulgarian Journal of Agricultural Science",
title = "Study of the growth traits relationship of lambs in the postnatal development",
volume = "19",
number = "4",
pages = "801-805",
url = "https://hdl.handle.net/21.15107/rcub_ristocar_377"
}

Caro Petrović, V., Ilić, Z. Z., Teneva, A., Petrović, M. P., Spasic, Z.L.J., Petrović, M. M.,& Ružić-Muslić, D.. (2013). Study of the growth traits relationship of lambs in the postnatal development. in Bulgarian Journal of Agricultural Science
Scientific Issues Natl Centre Agrarian Sciences, Sofia., 19(4), 801-805.
https://hdl.handle.net/21.15107/rcub_ristocar_377

Caro Petrović V, Ilić ZZ, Teneva A, Petrović MP, Spasic Z, Petrović MM, Ružić-Muslić D. Study of the growth traits relationship of lambs in the postnatal development. in Bulgarian Journal of Agricultural Science. 2013;19(4):801-805.
https://hdl.handle.net/21.15107/rcub_ristocar_377 .

Caro Petrović, Violeta, Ilić, Zoran Z., Teneva, A., Petrović, Milan P., Spasic, Z.L.J., Petrović, Milan M., Ružić-Muslić, Dragana, "Study of the growth traits relationship of lambs in the postnatal development" in Bulgarian Journal of Agricultural Science, 19, no. 4 (2013):801-805,
https://hdl.handle.net/21.15107/rcub_ristocar_377 .

TY  - JOUR
AU  - Teneva, A.
AU  - Petrović, Milan P.
PY  - 2010
UR  - http://r.istocar.bg.ac.rs/handle/123456789/245
AB  - With recent developments in DNA technologies, a large number of genetic polymorphisms at DNA sequence level has been introduced over the last decades as named DNA-based markers. The discovery of new class of DNA profiling markers has facilitated the development of marker-based gene tags, mapbased cloning of livestock important genes, variability studies, phylogenetic analysis, synteny mapping, marker-assisted selection of favourable genotypes, etc. The most commonly used DNA-based markers have advantages over the traditional phenotypic and biochemical markers since they provide data that can be analyzed objectively. In this article the main applications of molecular markers in present-day breeding strategies for livestock improvement - parentage determination, genetic distance estimation, genetic diversity, gene mapping and marker-assisted selection have been reviewed.
AB  - Sa razvojem DNK tehnologija, veliki broj genetskih polimorfizama na nivou DNK sekvence su predstavljene poseldnjih godina pod nazivom DNK markeri. Otkriće novih klasa DNK markera je olakšalo razvoj marker gena, kloniranja gena od važnosti u stočarstvu i to na bazi mapa, ispitivanje varijabilnosti, filogenetske analize, mapiranja, selekcije poželjnih genotipova pomoću markera, itd. Markeri na bazi DNK koji se najčešće koriste imaju prednost u odnosu na tradicionalne fenotiske i biohemijske markere jer obezbeđuju podatke koji se mogu objektivno analizirati. U ovom radu su predstavljeni načini korišćenja i aplikacija molekularnih markera u postojećim odgajivačkim strategijama odn. napretku stočarstva - određivanje porekla, ocena genetske distance, genetskog diverziteta, mapiranje gena i selekcija pomoću markera.
PB  - Institute for Animal Husbandry, Belgrade
T2  - Biotechnology in Animal Husbandry
T1  - Application of molecular markers in livestock improvement
T1  - Primena molekularnih markera u napretku stočarstva
VL  - 26
IS  - 3-4
SP  - 135
EP  - 154
DO  - 10.2298/BAH1004135T
ER  - 

@article{
author = "Teneva, A. and Petrović, Milan P.",
year = "2010",
abstract = "With recent developments in DNA technologies, a large number of genetic polymorphisms at DNA sequence level has been introduced over the last decades as named DNA-based markers. The discovery of new class of DNA profiling markers has facilitated the development of marker-based gene tags, mapbased cloning of livestock important genes, variability studies, phylogenetic analysis, synteny mapping, marker-assisted selection of favourable genotypes, etc. The most commonly used DNA-based markers have advantages over the traditional phenotypic and biochemical markers since they provide data that can be analyzed objectively. In this article the main applications of molecular markers in present-day breeding strategies for livestock improvement - parentage determination, genetic distance estimation, genetic diversity, gene mapping and marker-assisted selection have been reviewed., Sa razvojem DNK tehnologija, veliki broj genetskih polimorfizama na nivou DNK sekvence su predstavljene poseldnjih godina pod nazivom DNK markeri. Otkriće novih klasa DNK markera je olakšalo razvoj marker gena, kloniranja gena od važnosti u stočarstvu i to na bazi mapa, ispitivanje varijabilnosti, filogenetske analize, mapiranja, selekcije poželjnih genotipova pomoću markera, itd. Markeri na bazi DNK koji se najčešće koriste imaju prednost u odnosu na tradicionalne fenotiske i biohemijske markere jer obezbeđuju podatke koji se mogu objektivno analizirati. U ovom radu su predstavljeni načini korišćenja i aplikacija molekularnih markera u postojećim odgajivačkim strategijama odn. napretku stočarstva - određivanje porekla, ocena genetske distance, genetskog diverziteta, mapiranje gena i selekcija pomoću markera.",
publisher = "Institute for Animal Husbandry, Belgrade",
journal = "Biotechnology in Animal Husbandry",
title = "Application of molecular markers in livestock improvement, Primena molekularnih markera u napretku stočarstva",
volume = "26",
number = "3-4",
pages = "135-154",
doi = "10.2298/BAH1004135T"
}

Teneva, A.,& Petrović, M. P.. (2010). Application of molecular markers in livestock improvement. in Biotechnology in Animal Husbandry
Institute for Animal Husbandry, Belgrade., 26(3-4), 135-154.
https://doi.org/10.2298/BAH1004135T

Teneva A, Petrović MP. Application of molecular markers in livestock improvement. in Biotechnology in Animal Husbandry. 2010;26(3-4):135-154.
doi:10.2298/BAH1004135T .

Teneva, A., Petrović, Milan P., "Application of molecular markers in livestock improvement" in Biotechnology in Animal Husbandry, 26, no. 3-4 (2010):135-154,
https://doi.org/10.2298/BAH1004135T . .